M.bennett at 03:03, 3 January 2021

2021-01-03T03:03:35Z

M.bennett at 01:47, 4 May 2020

2020-05-04T01:47:38Z

M.bennett: Created page with " '''Muscle pain and markers of muscle damage were improved after a course of hyperbaric oxyge..."

2020-05-04T01:42:11Z

Created page with " '''Muscle pain and markers of muscle damage were improved after a course of hyperbaric oxyge..."

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'''Muscle pain and markers of muscle damage were improved after a course of hyperbaric oxygen therapy'''

'''Clinical Bottom Line:'''

1. HBOT reduced some markers of muscle injury

2. HBOT resulted in lower pain scores after ten treatments for muscle strain injuries in athletes.

 

'''Citation/s:'''1.Chen CY, Chou WY, Ko JY, Lee MS, Wu RW. Early recovery of exercise-related muscular injury by HBOT. BioMed Research International. 6289380; 2019

'''Lead author's name and fax:'''Re-Wen Wu: ray4595@gmail.com

 

'''Three-part Clinical Question:'''In elite athletes, does exposure to hyperbaric oxygen compared to standard approaches, promote recovery from muscular injury?

'''Search Terms:''' Athletes; recovery; pain

 

'''The Study:'''

Double-blinded concealed randomised controlled trial with intention-to-treat.

'''The Study Patients:'''  Adult baseball players with minor muscle strains lasting more than two weeks that did not interrupt their athletic schedule.

Control group (N = 23; 21 analysed): Sham treatment breathing air at 1.3ATA on the same time schedule as the experimental group.

Experimental group (N = 23; 20 analysed): 100% oxygen breathing at 2.5 ATA for 60m minutes daily for 10 days.

'''The Evidence:'''

{| class="Table" style="border:undefined"
|-
| rowspan="2" style="width:153.3pt" width="207" | '''Measure'''
| colspan="2" style="width:90.65pt" width="123" | '''Sham Group'''
| colspan="2" style="width:83.55pt" width="114" | '''HBOT Group'''
| rowspan="2" style="width:55.2pt" width="76" | '''Difference'''
| rowspan="2" style="width:69.35pt" width="95" | '''95% CI'''
|-
| style="width:48.1pt" width="66" | '''Mean'''
| style="width:41.05pt" width="57" | '''SD'''
| style="width:26.85pt" width="38" | '''Mean'''
| style="width:55.2pt" width="76" | '''SD'''
|-
| style="width:153.3pt" width="207" |
'''Serum creatine phosphokinase (U/L) at end of 10 treatments'''

| style="width:48.1pt" width="66" | 327.1
| style="width:41.05pt" width="57" | 181.1
| style="width:26.85pt" width="38" | 158.5
| style="width:55.2pt" width="76" | 78.0
| style="width:55.2pt" width="76" | 168.6
| style="width:69.35pt" width="95" | -158.8 to 192.8
|-
| style="width:153.3pt" width="207" |
'''Myoglobin (ng/mL) at end of 10 treatments'''

| style="width:48.1pt" width="66" | 43.3
| style="width:41.05pt" width="57" | 19.4
| style="width:26.85pt" width="38" | 19.4
| style="width:55.2pt" width="76" | 10.2
| style="width:55.2pt" width="76" | 25.3
| style="width:69.35pt" width="95" | -92.6 to 143.2
|-
| style="width:153.3pt" width="207" |
'''Pain on average in the last week (0 to 10 scale) at end of 10 treatments'''

| style="width:48.1pt" width="66" | 3.5
| style="width:41.05pt" width="57" | 1.6
| style="width:26.85pt" width="38" | 1.8
| style="width:55.2pt" width="76" | 1.6
| style="width:55.2pt" width="76" | 8.29
| style="width:69.35pt" width="95" | -49.7 to 66.3
|}
 
 
'''Comments:'''
1. Generally high-quality study with good randomisation and blinding

2. Study was powered at 80% to show a difference of 12.9 on the 'Brief Pain Inventory'. This appears to be a combination of seven pain dimensions for pain intensity and effect on life, but that result is not given in the paper - only the individual element scores.

3. Elements of the BPI were all less than 5 and we have presumed these are out of a maximum score of 10.

4. These results are at odds with previously published data- this may reflect a different demographic and the grade and chronicity of injury

'''Appraised by:'''Mike Bennett; Sunday, 26 April 2020

'''Email: '''m.bennett@unsw.edu.au

Kill or Update By:  April 2023

Chen - Revision history

M.bennett at 03:03, 3 January 2021

M.bennett at 01:47, 4 May 2020

M.bennett: Created page with " '''Muscle pain and markers of muscle damage were improved after a course of hyperbaric oxyge..."