M.bennett at 06:06, 30 September 2021

2021-09-30T06:06:26Z

M.bennett at 05:49, 6 February 2021

2021-02-06T05:49:51Z

M.bennett at 05:48, 6 February 2021

2021-02-06T05:48:07Z

M.bennett: Created page with " '''For sudden hearing lo..."

2021-02-06T05:41:33Z

Created page with " '''For sudden hearing lo..."

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'''For sudden hearing loss, the addition of hyperbaric oxygen at both daily and twice-daily schedules to 20 total treatments resulted in improved outcomes compared to standard treatment alone.'''

'''Clinical bottom line:'''

{| class="Table" style="width: 882px;" width="583"
|- style="height:59.05pt"
| style="width: 870px;" |
'''1. There was a greater improvement in the proportion of patients with an effective response in the hyperbaric groups. 2. The mean improvement in hearing loss thresholds was greater with hyperbaric.'''

|}

'''Citation/s:'''1. Hu Y, Chen H, Xiong J, Sun W. [The efficacy of hyperbaric oxygen in the treatment of sudden sensorineural hearing loss]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jun;34(6):521-523;527.  

'''Lead author's name and fax:'''Chen Hongjiang, E-mail:13637809328@163.com

'''Three-part Clinical Question:'''For patients with ISSNHL, does the addition of hyperbaric oxygen to medical therapy result in improved hearing outcome? '''Search Terms:''' Hearing loss; steroids; intensive course

'''The Study:'''Non-blinded randomised controlled trial without intention-to-treat. '''The Study Patients:''' No details given except the diagnosis of 'sudden sensorineural hearing loss'. '''Control group''' (N = 42; 42 analysed): Standard medical management in this institution (14 day course, no details given). '''Experimental group''' (N = 65; 65 analysed): Either daily hyperbaric treatment or twice daily treatment to a total of 20 sessions - details not given.

'''The Evidence:'''

{| class="Table" style="border: 1pt solid windowtext; width: 809px;"
|-
| style="width: 159px; border: 1pt solid windowtext;" width="110" | '''Outcome'''
| style="width: 81px; border: 1pt solid windowtext;" width="66" | '''Time to Outcome'''
| style="width: 71px; border: 1pt solid windowtext;" width="57" | '''Control group'''
| style="width: 76px; border: 1pt solid windowtext;" width="51" | '''HBO group'''
| style="width: 128px; border: 1pt solid windowtext;" width="92" | '''Relative risk reduction'''
| style="width: 128px; border: 1pt solid windowtext;" width="121" | '''Absolute risk reduction'''
| style="width: 112px; border: 1pt solid windowtext;" width="88" | '''NNT'''
|-
| rowspan="2" style="width: 159px; border: 1pt solid windowtext;" width="110" | '''Effective treatment (not defined)'''
| style="width: 81px; border: 1pt solid windowtext;" width="66" | 20 days
| style="width: 71px; border: 1pt solid windowtext;" width="57" | 0.62
| style="width: 76px; border: 1pt solid windowtext;" width="51" | 0.80
| style="width: 128px; border: 1pt solid windowtext;" width="92" | 29%
| style="width: 128px; border: 1pt solid windowtext;" width="121" | 0.18
| style="width: 112px; border: 1pt solid windowtext;" width="88" | 6
|-
| colspan="3" style="width: 242px; border: 1pt solid windowtext;" width="178" | 95% CIs:
| style="width: 128px; border: 1pt solid windowtext;" width="92" | 1% to 58%
| style="width: 128px; border: 1pt solid windowtext;" width="121" | 0.005 to 0.36
| style="width: 112px; border: 1pt solid windowtext;" width="88" | 3 to 206
|}

 

{| class="Table" style="border:solid windowtext 1.0pt"
|-
| rowspan="2" style="border:solid windowtext 1.0pt" | '''Measure'''
| colspan="2" style="width:85.2pt; border:solid windowtext 1.0pt" width="114" | '''Control Group'''
| colspan="2" style="width:85.8pt; border:solid windowtext 1.0pt" width="114" | '''HBO Group'''
| rowspan="2" style="width:69.35pt; border:solid windowtext 1.0pt" width="92" | '''Difference'''
| rowspan="2" style="width:80.25pt; border:solid windowtext 1.0pt" width="107" | '''95% CI'''
|-
| style="width:37.25pt; border:solid windowtext 1.0pt" width="50" | '''Mean'''
| style="width:46.45pt; border:solid windowtext 1.0pt" width="62" | '''SD'''
| style="width:43.25pt; border:solid windowtext 1.0pt" width="58" | '''Mean'''
| style="width:41.05pt; border:solid windowtext 1.0pt" width="55" | '''SD'''
|-
| style="border:solid windowtext 1.0pt" |
'''Mean hearing recovery at 20 days (dB threshold)'''

| style="width:37.25pt; border:solid windowtext 1.0pt" width="50" | 17.6
| style="width:46.45pt; border:solid windowtext 1.0pt" width="62" | 18.5
| style="width:43.25pt; border:solid windowtext 1.0pt" width="58" | 27.2
| style="width:41.05pt; border:solid windowtext 1.0pt" width="55" | 17.6
| style="width:69.35pt; border:solid windowtext 1.0pt" width="92" | 9.60
| style="width:80.25pt; border:solid windowtext 1.0pt" width="107" | 116.9 to 136.1
|}

'''Comments:''' 1. Full report in Chinese. This information taken from abstract. 2. Pseudorandom allocation by sequential allocation to groups (this does not explain the disparity in group sizes).

3. Awaiting full translation. Wide confidence limits.

'''Appraised by:'''Mike Bennett Email m.bennett@unsw.edu.au; Saturday, 6 February 2021 '''Kill or Update By:''' February 2022

@@ Line 10: / Line 10: @@
 |}
 <span style="line-height:normal">'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">Citation/s:</span></span></span>'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">1. Hu Y, Chen H, Xiong J, Sun W. [The efficacy of hyperbaric oxygen in the treatment of sudden sensorineural hearing loss]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jun;34(6):521-523;527. &nbsp;</span></span></span></span>
@@ Line 75: / Line 77: @@
 <span style="line-height:normal"><span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">3. Awaiting full translation. Wide confidence limits.</span></span></span></span>
-<span style="line-height:normal">'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">Appraised by:</span></span></span>'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">Mike Bennett Email m.bennett@unsw.edu.au; Saturday, 6 February 2021<br/> '''Kill or Update By:''' February 2022</span></span></span></span>
+<span style="line-height:normal">'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">Appraised by:</span></span></span>'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">Mike Bennett Email m.bennett@unsw.edu.au; Saturday, 6 February 2021<br/> '''Kill or Update By:'''&nbsp;June&nbsp;2022</span></span></span></span>
-<p style="text-align: center;">&nbsp;</p> <p style="text-align: center;">&nbsp;</p> <p style="text-align: center;">http://hboevidence.wikis.unsw.edu.au/images/8/89/Sumhorsa.gif</p> <p style="text-align: center;">&nbsp;</p> <p style="text-align: center;"><span style="font-size:xx-large;">[http://hboevidence.wikis.unsw.edu.au/Audiovestibular BACK]</span></p>
+<p style="text-align: center;">&nbsp;</p> <p style="text-align: center;">&nbsp;</p> <p style="text-align: center;">http://hboevidence.wikis.unsw.edu.au/images/8/89/Sumhorsa.gif</p> <p style="text-align: center;">&nbsp;</p> <p style="text-align: center;"><span style="font-size:xx-large;">[[Audiovestibular|BACK]]</span></p>

← Older revision		Revision as of 05:49, 6 February 2021
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	<span style="line-height:normal">'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">Appraised by:</span></span></span>'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">Mike Bennett Email m.bennett@unsw.edu.au; Saturday, 6 February 2021<br/> '''Kill or Update By:''' February 2022</span></span></span></span>		<span style="line-height:normal">'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">Appraised by:</span></span></span>'''<span style="font-size:13.5pt"><span style="font-family:"><span style="color:black">Mike Bennett Email m.bennett@unsw.edu.au; Saturday, 6 February 2021<br/> '''Kill or Update By:''' February 2022</span></span></span></span>
−	<p style="text-align: center;"> </p> <p style="text-align: center;"></p> <p style="text-align: center;"> </p> <p style="text-align: center;"><span style="font-size:xx-large;">[http://hboevidence.wikis.unsw.edu.au/Audiovestibular BACK]</span></p>	+	<p style="text-align: center;"> </p> <p style="text-align: center;"> </p> <p style="text-align: center;">http://hboevidence.wikis.unsw.edu.au/images/8/89/Sumhorsa.gif</p> <p style="text-align: center;"> </p> <p style="text-align: center;"><span style="font-size:xx-large;">[http://hboevidence.wikis.unsw.edu.au/Audiovestibular BACK]</span></p>

Hu - Revision history

M.bennett at 06:06, 30 September 2021

M.bennett at 05:49, 6 February 2021

M.bennett at 05:48, 6 February 2021

M.bennett: Created page with " '''For sudden hearing lo..."