M.bennett at 07:25, 17 August 2022

2022-08-17T07:25:52Z

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M.bennett at 06:10, 22 July 2019

2019-07-22T06:10:15Z

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M.bennett at 06:07, 22 July 2019

2019-07-22T06:07:40Z

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Gordoben: Imported from Wikispaces

2017-11-15T06:57:13Z

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==Hyperbaric oxygen therapy following urethral reconstruction limited the decrease in erectile function==
===Clinical bottom line:===

{|
| '''1. Erectile function scores declined less following postoperative HBOT than a sham treatment.'''
|-
|}
**Citation/s:'''
1. Yuan J-B, Yang L-Y, Wang Y-H, Ding T, Chen TD, Lu Q. Hyperbaric oxygen therapy for recovery of erectile function after posterior urethral reconstruction. International Urology Journal 2011; 43:755-761

**Lead author's name and fax:''' Yang: yang_louyan@yahoo.cn
**Three-part Clinical Question:''' Does hyperbaric oxygen promote the recovery of erectile function following posterior urethral reconstruction.

**Search Terms:''' erectile dysfunction. urethral reconstruction, urethral stricture
**The Study:''' Double-blinded pseudo-randomised trial (alternate allocation) with intention-to-treat.

**The Study Patients:''' Men with posterior urethral stricture and having operative reconstruction.
**Control group''' (N = 12; 12 analysed): Placed in chamber and breathing air at 1 ATA on the same schedule as for HBOT group.
**Experimental group''' (N = 12; 12 analysed): 100% oxygen breathing at 2 ATA for 90 minutes daily postoperatively from the second postoperative day for a total of 14 treatments.

**The Evidence:'''
{|
| '''Measure''' |||| '''Air Group''' |||| '''HBOT group''' || '''Difference''' || '''95% CI'''
|-
|^ || '''Mean''' || '''SD''' || '''Mean''' || '''SD''' || ||
|-
| '''Total IIEF* scores at 3 months (score 0 worst - 70 best) ''' || 52.8 || 5.2 || 61.3 || 4.1 || -8.5 || -12.4 to -4.6
|-
| '''Erectile function domain at 3 months (0 - 25)''' || 19.5 || 2.9 || 23.8 || 1.9 || -4.3 || -6.3 to -2.2
|-
|}
*IIEF = International Index of Erectile Function

**Comments:'''
1. Not truly randomized. Alternate allocation following reconstruction.
2. Patients with EF scores less than 22 (any degree of dysfunction) pre-operatively were excluded (2 pts).
3. Erectile function scores were worse in both groups postoperatively, but on comparison, those who received HBOT had better scores.
4. Unpressurized sham - not known if this was effective.
5. Only a three month study. Long term effects not known.

**Appraised by''': M Bennett m.bennett@unsw.edu.au ; Friday, 16 January 2015

**Kill or Update By:''' July 2021

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Yuan 2010 - Revision history

M.bennett at 07:25, 17 August 2022

M.bennett at 06:10, 22 July 2019

M.bennett at 06:07, 22 July 2019

Gordoben: Imported from Wikispaces