Difference between revisions of "Williamson"

 
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<span style="line-height:normal">'''<span style="font-size:18.0pt"><span style="font-family:" times="" new="" roman",serif"="">No data on the use of hyperbaric oxygen for open tibial fractures</span></span>'''</span>
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<span style="line-height:normal">'''<span style="font-size:18.0pt"><span style="font-family:">No data on the use of hyperbaric oxygen for open tibial fractures</span></span>'''</span>
  
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<span style="line-height:normal">'''<span style="font-size:14.0pt"><span style="font-family:" times="" new="" roman",serif"="">Clinical bottom line:</span></span>'''</span>
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<span style="line-height:normal">'''<span style="font-size:14.0pt"><span style="font-family:">Clinical bottom line:</span></span>'''</span>
  
 
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<span style="line-height:normal"><span style="font-size:14.0pt"><span style="font-family:" times="" new="" roman",serif"="">1. Trial abandoned having recruited only 17 patients in total (target 36 in each group)</span></span></span>
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<span style="line-height:normal"><span style="font-size:14.0pt"><span style="font-family:">1. Trial abandoned having recruited only 17 patients in total (target 36 in each group)</span></span></span>
  
 
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Citation/s:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">1. Williamson OD, Millar I, Venturoni C. Hyperbaric oxygen and the management of open tibial fractures. Journal of Bone and Joint Surgery – British Volume, Orthopaedic proceedings 2005; 88-B(Suppl II):323.</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Citation/s:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">1. Williamson OD, Millar I, Venturoni C. Hyperbaric oxygen and the management of open tibial fractures. Journal of Bone and Joint Surgery – British Volume, Orthopaedic proceedings 2005; 88-B(Suppl II):323.</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Lead author's name and fax:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">I. Millar I.Millar@alfred.org.au</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Lead author's name and fax:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">I. Millar I.Millar@alfred.org.au</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Three-part Clinical Question:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Does HBOT improve soft tissue healing in adult patients with open tibial fractures?</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Three-part Clinical Question:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">Does HBOT improve soft tissue healing in adult patients with open tibial fractures?</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Search Terms:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Open tibial fracture; crush injury</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Search Terms:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">Open tibial fracture; crush injury</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">The Study:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Non-blinded randomised controlled trial.</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">The Study:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">Non-blinded randomised controlled trial.</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">The Study Patients:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Adults with lower leg fractures requiring extensive soft tssue and/or vascular repair (Gustillo class 3B and 3C fractures).</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">The Study Patients:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">Adults with lower leg fractures requiring extensive soft tssue and/or vascular repair (Gustillo class 3B and 3C fractures).</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Control group:''</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">No HBOT, usual management.</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Control group:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">No HBOT, usual management.</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Experimental group:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">As above plus HBOT – dose not reported.</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Experimental group:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">As above plus HBOT – dose not reported.</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">The Evidence:</span></span>'''</span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">The Evidence:</span></span>'''</span>
  
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<span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">None reported.</span></span></span>
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<span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:">None reported.</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Comments:</span></span>'''</span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Comments:</span></span>'''</span>
  
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<span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">1. Reasons for cancellation given were slower than expected recruitment rate and difficulty engaging orthopaedic team owing to pre-existing belief that HBO was efficacious.</span></span></span>
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<span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:">1. Reasons for cancellation given were slower than expected recruitment rate and difficulty engaging orthopaedic team owing to pre-existing belief that HBO was efficacious.</span></span></span>
  
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<span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">2. No report of any outcome from the 17 enrolled patients.</span></span></span>
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<span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:">2. No report of any outcome from the 17 enrolled patients.</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Appraised by:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Craig Wilson c.c.wilson@live.co.uk; Friday, 24 November 2017</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Appraised by:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">Craig Wilson c.c.wilson@live.co.uk; Friday, 24 November 2017</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Email:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">c.c.wilson@live.co.uk</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Email:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">c.c.wilson@live.co.uk</span></span></span>
  
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Kill or Update By:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">November 2022</span></span></span>
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">Kill or Update By:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:">November 2022</span></span></span>
  
 
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Latest revision as of 22:56, 23 August 2022

No data on the use of hyperbaric oxygen for open tibial fractures

Clinical bottom line:

1. Trial abandoned having recruited only 17 patients in total (target 36 in each group)


Citation/s:1. Williamson OD, Millar I, Venturoni C. Hyperbaric oxygen and the management of open tibial fractures. Journal of Bone and Joint Surgery – British Volume, Orthopaedic proceedings 2005; 88-B(Suppl II):323.

Lead author's name and fax:I. Millar I.Millar@alfred.org.au

Three-part Clinical Question:Does HBOT improve soft tissue healing in adult patients with open tibial fractures?

Search Terms:Open tibial fracture; crush injury

The Study:Non-blinded randomised controlled trial.

The Study Patients:Adults with lower leg fractures requiring extensive soft tssue and/or vascular repair (Gustillo class 3B and 3C fractures).

Control group:No HBOT, usual management.

Experimental group:As above plus HBOT – dose not reported.

The Evidence:

None reported.

Comments:

1. Reasons for cancellation given were slower than expected recruitment rate and difficulty engaging orthopaedic team owing to pre-existing belief that HBO was efficacious.

2. No report of any outcome from the 17 enrolled patients.

Appraised by:Craig Wilson c.c.wilson@live.co.uk; Friday, 24 November 2017

Email:c.c.wilson@live.co.uk

Kill or Update By:November 2022

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