Difference between revisions of "Meng"

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==Eating a dried salted plum during compression reduced the incidence of moderate to severe ear pain during compression==
 
  
==<span style="font-size: 12pt;">Clinical bottom line:</span>==
+
<span style="line-height:normal">'''<span style="font-size:18.0pt"><span style="font-family:" times="" new="" roman",serif"="">Eating a dried salted plum during compression reduced the incidence of moderate to severe ear pain during compression</span></span>'''</span>
{|
+
 
| '''<span style'''"font-size: 120%;">1. The proportion of patients complaining of moderate to severe ear pain was reduced when compressed while eating a dried salted plum.</span>'''<br><br>**<span style'''"font-size: 120%;"> 2. There was no reduction in otoscopic assessment of the severity of middle ear barotrauma </span>'''  
+
<span style="line-height:normal">'''<span style="font-size:14.0pt"><span style="font-family:" times="" new="" roman",serif"="">Clinical bottom line:</span></span>'''</span>
 +
 
 +
{| class="Table" style="border:undefined"
 
|-
 
|-
 +
|
 +
<span style="line-height:normal"><span style="font-size:14.0pt"><span style="font-family:" times="" new="" roman",serif"="">1. The proportion of patients complaining of moderate to severe ear pain was reduced when compressed while eating a dried salted plum.</span></span><br/> <br/> <span style="font-size:14.0pt"><span style="font-family:" times="" new="" roman",serif"="">2. There was no reduction in otoscopic assessment of the severity of middle ear barotrauma</span></span></span>
 +
 
|}
 
|}
  
**<span style="font-size: 120%;">Citation/s: </span>'''
+
----
<span style="font-size: 120%;">1. Meng FC, Shen CH, Wu D, Chu CM, Shih CP, Lin HC, Peng CK, Chang SC, Huang KL. Dried salted plum consumption ameliorates hyperbaric oxygen therapy-induced otalgia severity at the first chamber session: a prospective randomized controlled study. Undersea & hyperbaric medicine: journal of the Undersea and Hyperbaric Medical Society, Inc. 2017;44(6):551-7.</span>
 
  
<span style="font-size: 120%;">'''Lead author's name and fax:''' Chih-Hao Shen, MD – potato652@yahoo.com.tw</span>
+
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Citation/s:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">1. Meng FC, Shen CH, Wu D, Chu CM, Shih CP, Lin HC, Peng CK, Chang SC, Huang KL. Dried salted plum consumption ameliorates hyperbaric oxygen therapy-induced otalgia severity at the first chamber session: a prospective randomized controlled study. Undersea & hyperbaric medicine: journal of the Undersea and Hyperbaric Medical Society, Inc. 2017;44(6):551-7.</span></span></span>
<span style="font-size: 120%;">'''Three-part Clinical Question:''' During an initial compression for hyperbaric oxygen delivery, does eating a dried salted plum versus doing nothing specific result in any reduction in otalgia from middle ear barotrauma?</span>
 
  
<span style="font-size: 120%;">'''Search Terms:''' Middle ear barotrauma; prevention; Valsalva</span>
+
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Lead author's name and fax:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Chih-Hao Shen, MD – potato652@yahoo.com.tw</span></span></span>
  
**<span style="font-size: 120%;">The Study: </span>'''<span style="font-size: 120%;">Non-blinded randomised controlled trial with intention-to-treat. </span>
+
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Three-part Clinical Question:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">During an initial compression for hyperbaric oxygen delivery, does eating a dried salted plum versus doing nothing specific result in any reduction in otalgia from middle ear barotrauma?</span></span></span>
<span style="font-size: 120%;">'''The Study Patients:''' Adult patients undergoing their first compression for the purpose of delivering hyperbaric oxygen therapy </span>
 
<span style="font-size: 120%;">'''Control group''' (N = 37; 37 analysed): Patients underwent a 15 minute compression from 1 ATA to 2.5 ATA after instructions on clearing ears. </span>
 
<span style="font-size: 120%;">'''Experimental group''' (N = 53; 53 analysed): As above but patients were also asked to eat a dried salted plum during compression</span>
 
  
**<span style="font-size: 120%;">The Evidence:</span>'''
+
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Search Terms:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Middle ear barotrauma; prevention; Valsalva</span></span></span>
{|
+
 
| <span style'''"display: block; text-align: center;">'''<span style'''"font-size: 110%;">Outcome</span>'''</span> || <span style'''"display: block; text-align: center;">'''<span style'''"font-size: 110%;">Time to Outcome</span>'''</span> || <span style'''"display: block; text-align: center;">'''<span style'''"font-size: 110%;">Control Group</span>'''</span> || <span style'''"display: block; text-align: center;">'''<span style'''"font-size: 110%;">Plum Group</span>'''</span> || <span style'''"display: block; text-align: center;">'''<span style'''"font-size: 110%;">Relative risk reduction</span>'''</span> || <span style'''"display: block; text-align: center;">'''<span style'''"font-size: 110%;">Absolute risk reduction</span>'''</span> || <span style'''"display: block; text-align: center;">'''<span style'''"font-size: 110%;">NNT</span>'''</span>  
+
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">The Study:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Non-blinded randomised controlled trial with intention-to-treat.'''</span></span></span>
 +
 
 +
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">The Study Patients:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Adult patients undergoing their first compression for the purpose of delivering hyperbaric oxygen therapy</span></span></span>
 +
 
 +
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Control group</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">(N = 37; 37 analysed): Patients underwent a 15 minute compression from 1 ATA to 2.5 ATA after instructions on clearing ears.</span></span></span>
 +
 
 +
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Experimental group</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">(N = 53; 53 analysed): As above but patients were also asked to eat a dried salted plum during compression</span></span></span>
 +
 
 +
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">The Evidence:</span></span>'''</span>
 +
 
 +
{| class="Table" style="border:solid windowtext 1.0pt"
 
|-
 
|-
| <span style'''"display: block; text-align: center;">'''<span style'''"font-size: 10pt;">Otoscopic signs of severe (Grade 3 to 4) MEB (Teed score 0 to 5 worst) </span>'''</span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">30 mins</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">0.19</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">0.19</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">0%</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">0.0</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">INF</span></span>  
+
| style="border: 1pt solid windowtext; width: 272px;" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Outcome</span></span>'''</span></p>
 +
| style="width: 93px; border: 1pt solid windowtext;" width="68" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Time to Outcome</span></span>'''</span></p>
 +
| style="width: 93px; border: 1pt solid windowtext;" width="59" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Control Group</span></span>'''</span></p>
 +
| style="width: 69px; border: 1pt solid windowtext;" width="56" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Plum Group</span></span>'''</span></p>
 +
| style="width: 122px; border: 1pt solid windowtext;" width="95" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Relative risk reduction</span></span>'''</span></p>
 +
| style="width: 110px; border: 1pt solid windowtext;" width="94" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Absolute risk reduction</span></span>'''</span></p>
 +
| style="width: 107px; border: 1pt solid windowtext;" width="72" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">NNT</span></span>'''</span></p>  
 
|-
 
|-
|^  |||||| <span style'''"display: block; text-align: right;"><span style'''"font-size: 110%;">95% CIs:</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">-87% to 87%</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">-0.16 to 0.16</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">NNT ''' 6 to INF; </span></span><br><span style'''"display: block; text-align: center;"><span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">NNH ''' 6 to IN</span><span style'''"font-size: 9pt;">F</span></span></span>  
+
| rowspan="2" style="border: 1pt solid windowtext; width: 272px;" |  
 +
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Otoscopic signs of severe (Grade 3 to 4) MEB (Teed score 0 to 5 worst)</span></span>'''</span>
 +
 
 +
| style="width: 93px; border: 1pt solid windowtext;" width="68" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">30 mins</span></span></span></p>
 +
| style="width: 93px; border: 1pt solid windowtext;" width="59" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">0.19</span></span></span></p>
 +
| style="width: 69px; border: 1pt solid windowtext;" width="56" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">0.19</span></span></span></p>
 +
| style="width: 122px; border: 1pt solid windowtext;" width="95" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">0%</span></span></span></p>  
 +
| style="width: 110px; border: 1pt solid windowtext;" width="94" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">0.0</span></span></span></p>
 +
| style="width: 107px; border: 1pt solid windowtext;" width="72" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">INF</span></span></span></p>  
 
|-
 
|-
| <span style'''"display: block; text-align: center;">'''<span style'''"font-size: 10pt;">Moderate to severe otalgia, VAS >3 (VAS 0 to 10 worst) </span>'''</span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">30 mins </span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">0.11</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">0</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">100%</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">0.108</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">9</span></span>  
+
| colspan="3" style="width: 269px; border: 1pt solid windowtext;" width="182" | <p align="right" style="margin-bottom:.0001pt; text-align:right; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">95% CIs:</span></span></span></p>
 +
| style="width: 122px; border: 1pt solid windowtext;" width="95" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">-87% to 87%</span></span></span></p>
 +
| style="width: 110px; border: 1pt solid windowtext;" width="94" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">-0.16 to 0.16</span></span></span></p>
 +
| style="width: 107px; border: 1pt solid windowtext;" width="72" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">NNT 6 to INF;<br/> NNH 6 to INF</span></span></span></p>  
 
|-
 
|-
|^  |||||| <span style'''"display: block; text-align: right;"><span style'''"font-size: 110%;">95% CIs:</span></span> ||   || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">0.01 to 0.21</span></span> || <span style'''"display: block; text-align: center;"><span style'''"font-size: 110%;">5 to 125</span></span>  
+
| rowspan="2" style="border: 1pt solid windowtext; width: 272px;" |  
 +
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Moderate to severe otalgia, VAS >3 (VAS 0 to 10 worst)</span></span>'''</span>
 +
 
 +
| style="width: 93px; border: 1pt solid windowtext;" width="68" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">30 mins</span></span></span></p>
 +
| style="width: 93px; border: 1pt solid windowtext;" width="59" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">0.11</span></span></span></p>
 +
| style="width: 69px; border: 1pt solid windowtext;" width="56" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">0</span></span></span></p>
 +
| style="width: 122px; border: 1pt solid windowtext;" width="95" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">100%</span></span></span></p>
 +
| style="width: 110px; border: 1pt solid windowtext;" width="94" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">0.108</span></span></span></p>
 +
| style="width: 107px; border: 1pt solid windowtext;" width="72" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">9</span></span></span></p>  
 
|-
 
|-
 +
| colspan="3" style="width: 269px; border: 1pt solid windowtext;" width="182" | <p align="right" style="margin-bottom:.0001pt; text-align:right; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">95% CIs:</span></span></span></p>
 +
| style="width: 122px; border: 1pt solid windowtext; padding: 0.75pt;" width="95" | &nbsp;
 +
| style="width: 110px; border: 1pt solid windowtext;" width="94" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">0.01 to 0.21</span></span></span></p>
 +
| style="width: 107px; border: 1pt solid windowtext;" width="72" | <p align="center" style="margin-bottom:.0001pt; text-align:center; padding:.75pt .75pt .75pt .75pt"><span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">5 to 125</span></span></span></p>
 
|}
 
|}
**<span style="font-size: 120%;">Comments:</span>'''
 
 
<span style="font-size: 120%;">1. Not a surprising finding as the consumption of saliva-inducing food during compression has a long and venerable history of assisting ear clearing.</span>
 
 
<span style="font-size: 120%;">2. It is not quite clear what accounts for the difference in the number of patients allocated to each arm.</span>
 
  
<span style="font-size: 120%;">3. There seemed no close relationship between the Teed score and the degree of otalgia.</span>
+
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Comments:</span></span>'''</span>
  
<span style="font-size: 120%;">'''Appraised by:''' Mike Bennett; Monday, 21 January 2019</span>
+
<span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">1. Not a surprising finding as the consumption of saliva-inducing food during compression has a long and venerable history of assisting ear clearing.</span></span></span>
  
<span style="font-size: 120%;">'''Email:''' m.bennett@unsw.edu.au</span>
+
<span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">2. It is not quite clear what accounts for the difference in the number of patients allocated to each arm.</span></span></span>
  
<span style="font-size: 120%;">'''Kill or Update By''': June 2020</span>
+
<span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">3. There seemed no close relationship between the Teed score and the degree of otalgia.</span></span></span>
  
 +
<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Appraised by:</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Mike Bennett; Monday, 21 January 2019 '''Email:''' m.bennett@unsw.edu.au</span></span></span>
  
[[File:sumhorsa.gif|center|sumhorsa.gif]]
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<span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">Kill or Update By</span></span>'''<span style="font-size:12.0pt"><span style="font-family:" times="" new="" roman",serif"="">: June 2022</span></span></span>
  
 +
[[File:Sumhorsa.gif|center|sumhorsa.gif]]
  
 +
&nbsp;
  
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+
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Latest revision as of 02:01, 5 October 2021

Eating a dried salted plum during compression reduced the incidence of moderate to severe ear pain during compression

Clinical bottom line:

1. The proportion of patients complaining of moderate to severe ear pain was reduced when compressed while eating a dried salted plum.

2. There was no reduction in otoscopic assessment of the severity of middle ear barotrauma


Citation/s:1. Meng FC, Shen CH, Wu D, Chu CM, Shih CP, Lin HC, Peng CK, Chang SC, Huang KL. Dried salted plum consumption ameliorates hyperbaric oxygen therapy-induced otalgia severity at the first chamber session: a prospective randomized controlled study. Undersea & hyperbaric medicine: journal of the Undersea and Hyperbaric Medical Society, Inc. 2017;44(6):551-7.

Lead author's name and fax:Chih-Hao Shen, MD – potato652@yahoo.com.tw

Three-part Clinical Question:During an initial compression for hyperbaric oxygen delivery, does eating a dried salted plum versus doing nothing specific result in any reduction in otalgia from middle ear barotrauma?

Search Terms:Middle ear barotrauma; prevention; Valsalva

The Study:Non-blinded randomised controlled trial with intention-to-treat.

The Study Patients:Adult patients undergoing their first compression for the purpose of delivering hyperbaric oxygen therapy

Control group(N = 37; 37 analysed): Patients underwent a 15 minute compression from 1 ATA to 2.5 ATA after instructions on clearing ears.

Experimental group(N = 53; 53 analysed): As above but patients were also asked to eat a dried salted plum during compression

The Evidence:

Outcome

Time to Outcome

Control Group

Plum Group

Relative risk reduction

Absolute risk reduction

NNT

Otoscopic signs of severe (Grade 3 to 4) MEB (Teed score 0 to 5 worst)

30 mins

0.19

0.19

0%

0.0

INF

95% CIs:

-87% to 87%

-0.16 to 0.16

NNT 6 to INF;
NNH 6 to INF

Moderate to severe otalgia, VAS >3 (VAS 0 to 10 worst)

30 mins

0.11

0

100%

0.108

9

95% CIs:

 

0.01 to 0.21

5 to 125

Comments:

1. Not a surprising finding as the consumption of saliva-inducing food during compression has a long and venerable history of assisting ear clearing.

2. It is not quite clear what accounts for the difference in the number of patients allocated to each arm.

3. There seemed no close relationship between the Teed score and the degree of otalgia.

Appraised by:Mike Bennett; Monday, 21 January 2019 Email: m.bennett@unsw.edu.au

Kill or Update By: June 2022

sumhorsa.gif

 

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