Non-healing wounds

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NON-HEALING WOUNDS

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Including diabetic, vascular and infammatory bowel disease RTENOTITLE Subject last searched July 2018. Next search July 2021

Multiple Wound Aetiologies

Kranke P

Bennett M

Roeckl-
Wiedmann I

Hyperbaric therapy for chronic wounds (Cochrane Review)

Cochrane Database of Systematic Reviews 2015, Issue 6. Art. No.: CD004123. .pub4.

Diabetic foot

Venous ulcers

Arterial ulcers

Kaur S

Pawar M

Banerjee N

Evaluation of the efficacy of hyperbric oxygen therapy in the management of chronic nonhealing ulcer and role of periwound transcutaneous oximetry as a predictor of wound healing response: A randomised prospective controlled trial

Journal of Anaesthesiology and Clinical Pharmacology 2012; 28(1):70-75.

Diabetic foot

Venous ulcers

Transcutaneous oxymetry

Roeckl-
Wiedmann I

Bennett M

Kranke P

Systematic review of hyperbaric oxygen in the management of chronic wounds

British Journal of Surgery 2005;92:24-32

Diabetic Foot

Venous ulcers

Arterial ulcers

Diabetic Wounds

Doctor N

Pandya S

Supe A

Hyperbaric oxygen therapy in diabetic foot.

Journal of Postgraduate Medicine 1992; 38:112-114.

Diabetic angiopathies

Diabetic foot

Diabetic neuropathies

Faglia E

Favales F

Aldeghi A

Adjunctive systemic hyperbaric oxygen therapy in the treatment of diabetic foot ulcer. A randomized study.

Diabetes Care 1996;19:1338-43.

Diabetic foot

Diabetic angiopathies

Prognosis

Faglia E

Favales F

Aldeghi A

Adjunctive systemic hyperbaric oxygen therapy in the treatment of diabetic foot ulcer. A randomized study.

Proceedings of the International Joint Meeting on Hyperbaric and Underwater Medicine, Marroni A, Oriani G, Wattel F eds. Grafica Victoria, Bologna 1996; 391-399.

Diabetic foot

Diabetic angiopathies

Diabetic neuropathies

Kalani M

Naderi N

Lind F

Hyperbaric oxygen therapy for wound healing and limb salvage in diabetic foot lesions: three-year follow up.

Undersea and Hyperbaric Medicine 2000; 27(supl):44-45.

Diabetic angiopathies

 

Diabetic foot

Kalani M

Jorneskog G

Naderi N

Hyperbaric oxygen (HBO) therapy in treatment of diabetic foot ulcers. Long term follow-up.

Diabetes and its Complications 2002;16:153-158

Diabetic foot

 

Diabetic angiopathies

Lin TF

Chen SB

Niu KC

The vascular effects of hyperbaric oxygen therapy in treatment of early diabetic foot.

Undersea and Hyperbaric Medicine 2001; 28 (Suppl):67.

Diabetic foot

Diabetic angiopathies

Transcutaneous oximetry

Abidia A

Kuhan G

Laden G

Role of hyperbaric oxygen therapy in ischaemic, diabetic, lower extremity ulcers: a double-blind randomised controlled study.

British Journal of Surgery [Surgical Research Society Abstracts] 2001; 88(5):744

Diabetic foot

Amputation

Chronic wound

Abidia A

Kuhan G

Laden G

Hyperbaric oxygen therapy for diabetic leg ulcers - a Double-blinded randomised controlled trial.

Undersea and Hyperbaric Medicine 2001; 28(1): 48

Diabetic foot

   

Abidia A

Kuhan G

Laden G

Hyperbaric oxygen therapy for diabetic leg ulcers - a Double-blinded randomised controlled trial.

Undersea and Hyperbaric Medicine 2001; 28(Suppl): 64

Diabetic foot

Ulcers

 

Abidia A

Laden G

Kuhan G

The role of hyperbaric oxygen therapy in ischaemic diabetic lower extremity ulcers: a double-blind randomised-controlled trial.

European Journal of Vascular and Endovascular surgery 2003; 25:513-518

Diabetic foot

Ulcers

Amputation

Chin K

Xie Y

Abidia A

The relationship of hyperbaric oxygen therapy and vascular endothelial growth factor in diabetic patients with leg ulcers: a double blind randomised controlled trial.

Undersea and Hyperbaric Medicine 2001:28(Suppl);63

Diabetic foot

Ulcers

Vascular endothelial growth factor

Kessler L

Bilbault P

Ortega F

Hyperbaric oxygenation accelerates the healing rate of nonischemic chronic diabetic foot ulcers.

Diabetes Care 2003; 26:2378-82.

Diabetic Foot

Ulcers

Wound healing

Londahl M

Katzman P

Nilsson A

Hyperbaric oxygen therapy facilitates healing of chronic foot ulcers in patients with diabetes.

Diabetes Care 2010;33(5):998-1003.

Diabetic foot

Ulcers

Wound healing

Londahl M

Katzman M

Nilsson A

A prospective study: hyperbaric oxygen therapy in diabetics with chronic foot ulcers.

Journal of Wound Care 2006;10(15):457-459.

Diabetic foot

Ulcer

Chronic wounds

Londahl M

Ladin-Olssen M

Katzman P

Hyperbaric oxygen therapy improves health-related quality of life in patients with diabetes and chronic foot ulcer.

Diabetic Medicine 2011;28:186-190.

Diabetic foot

Quality of life

Ulcer

Londahl M

Ladin-Olssen M

Katzman P

Hyperbaric oxygen therapy improves health-related quality of life in patients with diabetes and chronic foot ulcer.

Diabetic Medicine 2011;28:186-190.

Diabetic foot

Quality of life

Ulcer

Londahl M

Fagher K

Nilsson AL

Improved 6-year survival in patients with chronic diabetic foot ulcers after hyperbaric oxygen therapy: outcome from a randomised double-blind study

Diabetologia 2015;58:S31-S32.

Diabetic foot

Transcutaneous oximetry

Survival

Ma L

Li P

She Z

A Prospective, Randomised Controlled Study of Hyperbaric Oxygen Therapy: Effects on Healing and Oxidative stress of Ulcer Tissue in Patients with a Diabetic Foot Ulcer. .

Ostomy Wound Management. 2013; 59 (3): 18 – 24

Diabetioc foot

Ulcer

Transcutaneous oximetry

Wang C-J

Wu R-W

Yang, Y-J

Treatment of diabetic foot ulcers: A comparative study of extracorporeal shockwave therapy and hyperbaric oxygen therapy.

Diabetes Research and Clinical Practice 2011;92(2):187-193

Diabetic foot

Extracorporeal shockwave therapy

Wound healing

Duzgun AP

Satir HZ

Ozozan O

Effect of hyperbaric oxygen therapy on healing of diabetic foot ulcers.

J of Foot & Ankle Surgery. 2008;47(6):515-9.

Diabetic foot

Ulcer

Amputation

Fedorko L

Bowen JM

Jones W

Hyperbaric Oxygen Therapy Does Not Reduce Indications for Amputation in Patients With Diabetes With Nonhealing Ulcers of the Lower Limb: A Prospective, Double-Blind, Randomized Controlled Clinical Trial.

Diabetes Care 2016; 39, 392-399.

Diabetic foot

Ulcer

Amputation

O'Reilly D

Linden R

Fedorko L

A prospective, double-blind, randomized, controlled clinical trial comparing standard wound care with adjunctive hyperbaric oxygen therapy (HBOT) to standard wound care only for the treatment of chronic, non-healing ulcers of the lower limb in patients with diabetes mellitus: a study protocol.

Trials. 2011 Mar 7;12:69. doi: 10.1186/1745-6215-12-69

Diabetic foot

Ulcer

Amputation

Perren S

Gatt A

Papanas N

Hyperbaric Oxygen Therapy in Ischemic Foot Ulcers in Type 2 Diabetes: A Clinical Trial.

The Open Cardiovascular Medicine Journal 2018; 12:80

Diabetic foot

Ulcer

Wound healing

Zhao D Luo S Xu W Efficacy and safety of hyperbaric oxygen therapy used in patients with diabetic foot: a meta-analysis of randomized clinical trials. Clinical therapeutics. 2017 Oct 1;39(10):2088-94. Diabetic foot Meta-analysis Wound healing
Salama SE Eldeeb AE Elbarbary AH  Adjuvant hyperbaric oxygen therapy enhances healing of nonischemic diabetic foot ulcers compared with standard wound care alone. The international journal of lower extremity wounds. 2019 Mar;18(1):75-80 Diabetic foot Ulcer  Wound healing
Khandelwal S Chaudhary P Poddar DD Comparative study of different treatment options of grade III and IV diabetic foot ulcers to reduce the incidence of amputations. Clinics and practice. 2013 Jan 25;3(1) Diabetic foot Ulcer Human recombinant growth factor
Santema KT Stoekenbroek RM Koelemay MJ Hyperbaric Oxygen Therapy in the Treatment of Ischemic Lower-Extremity Ulcers in Patients With Diabetes: Results of the DAMO2CLES Multicenter Randomized Clinical Trial. Diabetes care. 2018 Jan 1;41(1):112-9 Diabetic foot Ulcer Amputation
Li G Hopkins RB Levine MA Relationship between hyperbaric oxygen therapy and quality of life in participants with chronic diabetic foot ulcers: data from a randomized controlled trial. Acta diabetologica. 2017 Sep 1;54(9):823-31. Diabetic foot Ulcer Health Status
Chong SJ Kwan TM Weihao L Maintenance of negative-pressure wound therapy while undergoing hyperbaric oxygen therapy. Diving Hyperb Med. 2011 Sep;41(3):147-50 NPWD Diabetic foot Ulcer
Kumar A Shukla U Prabhakar T, Hyperbaric oxygen therapy as an adjuvant to standard therapy in the treatment of diabetic foot ulcers. Journal of Anaesthesiology, Clinical Pharmacology. 2020 Apr;36(2):213. Diabetic foot Wound care Amputation
 


 

Non Diabetic Wounds

Hammarlund C

Sundberg T

 

Hyperbaric oxygen reduced size of chronic leg ulcers: a randomized double-blind study.

Plastic and Reconstructive Surgery 1994; 93:829-834.

Leg ulcer

Wound healing

Chronic disease

Yildiz H

Senol L

Bilgili ME

A prospective randomized controlled trial assessing the efficacy of adjunctive hyperbaric oxygen therapy in the treatment of hidradenitis suppurativa.

International journal of dermatology. 2016;55(2):232-7.

Hydradenitis

Wound healing

HS

Thistlethwaite KR Finlayson KJ Cooper PD The effectiveness of hyperbaric oxygen therapy for healing chronic venous leg ulcers: A randomized, double-blind, placebo-controlled trial. Wound Repair and Regeneration. 2018 Jul;26(4):324-31 Leg ulcer Venous Wound healing
Thistlethwaite KR Finlayson KJ Cooper PD The Effectiveness of Hyperbaric Oxygen Therapy for Healing Chronic Venous Leg Ulcers: A Randomized, Double-Blind, Placebo-Controlled Trial. Journal of Vascular Surgery: Venous and Lymphatic Disorders. 2019 May 1;7(3):466 Leg ulcer Venous Wound healing

 

Inflammatory Bowel Disease

Dulai PS

Buckey JC

Raffals LE

Hyperbaric oxygen therapy is well tolerated and effective for ulcerative colitis patients hospitalized for moderate–severe flares:
a phase 2A pilot multi-center, randomized, double-blind, sham-controlled trial.

The American Journal of Gastroenterology 2018; Feb 16:1.

Ulcerative Colitis

Steroids

Hospitalisation

Pagoldh M

Hultgren E

Arnell P

Hyperbaric oxygen therapy does not improve the effects of standardized treatment in a severe attack of ulcerative colitis: a prospective randomized study.

Scand J Gastroenterol 2013; 48:1033-40

Ulcerative colitis

Steroids

Flare-up

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