Non-healing wounds
NON-HEALING WOUNDS
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Including diabetic, vascular and infammatory bowel disease Subject last searched July 2018. Next search July 2021
Multiple Wound Aetiologies
Bennett M |
Roeckl- |
Hyperbaric therapy for chronic wounds (Cochrane Review) |
Cochrane Database of Systematic Reviews 2015, Issue 6. Art. No.: CD004123. .pub4. |
Diabetic foot |
Venous ulcers |
Arterial ulcers | |
Pawar M |
Banerjee N |
Evaluation of the efficacy of hyperbric oxygen therapy in the management of chronic nonhealing ulcer and role of periwound transcutaneous oximetry as a predictor of wound healing response: A randomised prospective controlled trial |
Journal of Anaesthesiology and Clinical Pharmacology 2012; 28(1):70-75. |
Diabetic foot |
Venous ulcers |
Transcutaneous oxymetry | |
Bennett M |
Kranke P |
Systematic review of hyperbaric oxygen in the management of chronic wounds |
British Journal of Surgery 2005;92:24-32 |
Diabetic Foot |
Venous ulcers |
Arterial ulcers |
Diabetic Wounds
Pandya S |
Supe A |
Hyperbaric oxygen therapy in diabetic foot. |
Journal of Postgraduate Medicine 1992; 38:112-114. |
Diabetic angiopathies |
Diabetic foot |
Diabetic neuropathies | |
Favales F |
Aldeghi A |
Adjunctive systemic hyperbaric oxygen therapy in the treatment of diabetic foot ulcer. A randomized study. |
Diabetes Care 1996;19:1338-43. |
Diabetic foot |
Diabetic angiopathies |
Prognosis | |
Favales F |
Aldeghi A |
Adjunctive systemic hyperbaric oxygen therapy in the treatment of diabetic foot ulcer. A randomized study. |
Proceedings of the International Joint Meeting on Hyperbaric and Underwater Medicine, Marroni A, Oriani G, Wattel F eds. Grafica Victoria, Bologna 1996; 391-399. |
Diabetic foot |
Diabetic angiopathies |
Diabetic neuropathies | |
Naderi N |
Lind F |
Hyperbaric oxygen therapy for wound healing and limb salvage in diabetic foot lesions: three-year follow up. |
Undersea and Hyperbaric Medicine 2000; 27(supl):44-45. |
Diabetic angiopathies |
Diabetic foot | ||
Jorneskog G |
Naderi N |
Hyperbaric oxygen (HBO) therapy in treatment of diabetic foot ulcers. Long term follow-up. |
Diabetes and its Complications 2002;16:153-158 |
Diabetic foot |
Diabetic angiopathies | ||
Chen SB |
Niu KC |
The vascular effects of hyperbaric oxygen therapy in treatment of early diabetic foot. |
Undersea and Hyperbaric Medicine 2001; 28 (Suppl):67. |
Diabetic foot |
Diabetic angiopathies |
Transcutaneous oximetry | |
Kuhan G |
Laden G |
Role of hyperbaric oxygen therapy in ischaemic, diabetic, lower extremity ulcers: a double-blind randomised controlled study. |
British Journal of Surgery [Surgical Research Society Abstracts] 2001; 88(5):744 |
Diabetic foot |
Amputation |
Chronic wound | |
Kuhan G |
Laden G |
Hyperbaric oxygen therapy for diabetic leg ulcers - a Double-blinded randomised controlled trial. |
Undersea and Hyperbaric Medicine 2001; 28(1): 48 |
Diabetic foot |
|||
Kuhan G |
Laden G |
Hyperbaric oxygen therapy for diabetic leg ulcers - a Double-blinded randomised controlled trial. |
Undersea and Hyperbaric Medicine 2001; 28(Suppl): 64 |
Diabetic foot |
Ulcers |
||
Laden G |
Kuhan G |
The role of hyperbaric oxygen therapy in ischaemic diabetic lower extremity ulcers: a double-blind randomised-controlled trial. |
European Journal of Vascular and Endovascular surgery 2003; 25:513-518 |
Diabetic foot |
Ulcers |
Amputation | |
Xie Y |
Abidia A |
The relationship of hyperbaric oxygen therapy and vascular endothelial growth factor in diabetic patients with leg ulcers: a double blind randomised controlled trial. |
Undersea and Hyperbaric Medicine 2001:28(Suppl);63 |
Diabetic foot |
Ulcers |
Vascular endothelial growth factor | |
Bilbault P |
Ortega F |
Hyperbaric oxygenation accelerates the healing rate of nonischemic chronic diabetic foot ulcers. |
Diabetes Care 2003; 26:2378-82. |
Diabetic Foot |
Ulcers |
Wound healing | |
Katzman P |
Nilsson A |
Hyperbaric oxygen therapy facilitates healing of chronic foot ulcers in patients with diabetes. |
Diabetes Care 2010;33(5):998-1003. |
Diabetic foot |
Ulcers |
Wound healing | |
Katzman M |
Nilsson A |
A prospective study: hyperbaric oxygen therapy in diabetics with chronic foot ulcers. |
Journal of Wound Care 2006;10(15):457-459. |
Diabetic foot |
Ulcer |
Chronic wounds | |
Ladin-Olssen M |
Katzman P |
Hyperbaric oxygen therapy improves health-related quality of life in patients with diabetes and chronic foot ulcer. |
Diabetic Medicine 2011;28:186-190. |
Diabetic foot |
Quality of life |
Ulcer | |
Ladin-Olssen M |
Katzman P |
Hyperbaric oxygen therapy improves health-related quality of life in patients with diabetes and chronic foot ulcer. |
Diabetic Medicine 2011;28:186-190. |
Diabetic foot |
Quality of life |
Ulcer | |
Fagher K |
Nilsson AL |
Improved 6-year survival in patients with chronic diabetic foot ulcers after hyperbaric oxygen therapy: outcome from a randomised double-blind study |
Diabetologia 2015;58:S31-S32. |
Diabetic foot |
Transcutaneous oximetry |
Survival | |
Li P |
She Z |
A Prospective, Randomised Controlled Study of Hyperbaric Oxygen Therapy: Effects on Healing and Oxidative stress of Ulcer Tissue in Patients with a Diabetic Foot Ulcer. . |
Ostomy Wound Management. 2013; 59 (3): 18 – 24 |
Diabetioc foot |
Ulcer |
Transcutaneous oximetry | |
Wu R-W |
Yang, Y-J |
Treatment of diabetic foot ulcers: A comparative study of extracorporeal shockwave therapy and hyperbaric oxygen therapy. |
Diabetes Research and Clinical Practice 2011;92(2):187-193 |
Diabetic foot |
Extracorporeal shockwave therapy |
Wound healing | |
Satir HZ |
Ozozan O |
Effect of hyperbaric oxygen therapy on healing of diabetic foot ulcers. |
J of Foot & Ankle Surgery. 2008;47(6):515-9. |
Diabetic foot |
Ulcer |
Amputation | |
Bowen JM |
Jones W |
Hyperbaric Oxygen Therapy Does Not Reduce Indications for Amputation in Patients With Diabetes With Nonhealing Ulcers of the Lower Limb: A Prospective, Double-Blind, Randomized Controlled Clinical Trial. |
Diabetes Care 2016; 39, 392-399. |
Diabetic foot |
Ulcer |
Amputation | |
Linden R |
Fedorko L |
A prospective, double-blind, randomized, controlled clinical trial comparing standard wound care with adjunctive hyperbaric oxygen therapy (HBOT) to standard wound care only for the treatment of chronic, non-healing ulcers of the lower limb in patients with diabetes mellitus: a study protocol. |
Trials. 2011 Mar 7;12:69. doi: 10.1186/1745-6215-12-69 |
Diabetic foot |
Ulcer |
Amputation | |
Gatt A |
Papanas N |
Hyperbaric Oxygen Therapy in Ischemic Foot Ulcers in Type 2 Diabetes: A Clinical Trial. |
The Open Cardiovascular Medicine Journal 2018; 12:80 |
Diabetic foot |
Ulcer |
Wound healing | |
Zhao D | Luo S | Xu W | Efficacy and safety of hyperbaric oxygen therapy used in patients with diabetic foot: a meta-analysis of randomized clinical trials. | Clinical therapeutics. 2017 Oct 1;39(10):2088-94. | Diabetic foot | Meta-analysis | Wound healing |
Salama SE | Eldeeb AE | Elbarbary AH | Adjuvant hyperbaric oxygen therapy enhances healing of nonischemic diabetic foot ulcers compared with standard wound care alone. | The international journal of lower extremity wounds. 2019 Mar;18(1):75-80 | Diabetic foot | Ulcer | Wound healing |
Khandelwal S | Chaudhary P | Poddar DD | Comparative study of different treatment options of grade III and IV diabetic foot ulcers to reduce the incidence of amputations. | Clinics and practice. 2013 Jan 25;3(1) | Diabetic foot | Ulcer | Human recombinant growth factor |
Santema KT | Stoekenbroek RM | Koelemay MJ | Hyperbaric Oxygen Therapy in the Treatment of Ischemic Lower-Extremity Ulcers in Patients With Diabetes: Results of the DAMO2CLES Multicenter Randomized Clinical Trial. | Diabetes care. 2018 Jan 1;41(1):112-9 | Diabetic foot | Ulcer | Amputation |
Li G | Hopkins RB | Levine MA | Relationship between hyperbaric oxygen therapy and quality of life in participants with chronic diabetic foot ulcers: data from a randomized controlled trial. | Acta diabetologica. 2017 Sep 1;54(9):823-31. | Diabetic foot | Ulcer | Health Status |
Chong SJ | Kwan TM | Weihao L | Maintenance of negative-pressure wound therapy while undergoing hyperbaric oxygen therapy. | Diving Hyperb Med. 2011 Sep;41(3):147-50 | NPWD | Diabetic foot | Ulcer |
Kumar A | Shukla U | Prabhakar T, | Hyperbaric oxygen therapy as an adjuvant to standard therapy in the treatment of diabetic foot ulcers. | Journal of Anaesthesiology, Clinical Pharmacology. 2020 Apr;36(2):213. | Diabetic foot | Wound care | Amputation |
Sun TB | Yang CC | Kuo TB | Effect of hyperbaric oxygen on cardiac neural regulation in diabetic individuals with foot complications. | Diabet Med. 2006 Apr;23(4):360-6. | Diabetic foot | Autonomic function | Transcutaneous |
Efrati S | Gall N | Bergan J | Hyperbaric oxygen, oxidative stress, NO bioavailability and ulcer oxygenation in diabetic patient. | Undersea Hyperb Med. 2009 Jan-Feb;36(1):1-12 | Diabetic foot | NAC | Transcutaneous |
Sellman A | Katzman P | Andreasson S |
Long-term effects of hyperbaric oxygen therapy on visual acuity and retinopathy. |
Undersea & hyperbaric medicine: journal of the Undersea and Hyperbaric Medical Society, Inc. 2020 Jan 1;47(3):423-30. | Visual changes | Diabetic foot | Macular disease |
Wadee AN | Aref MH | Nassar AA |
The influence of low-intensity laser irradiation versus hyperbaric oxygen therapy on transcutaneous oxygen tension in chronic diabetic foot ulcers: a controlled randomised trial. |
Journal of Diabetes & Metabolic Disorders. 2021 Sep 3:1-9. | Diabetic foot | Wagner G 2 | Transcutaneous oxygen |
Non Diabetic Wounds
Sundberg T |
Hyperbaric oxygen reduced size of chronic leg ulcers: a randomized double-blind study. |
Plastic and Reconstructive Surgery 1994; 93:829-834. |
Leg ulcer |
Wound healing |
Chronic disease | ||
Senol L |
Bilgili ME |
A prospective randomized controlled trial assessing the efficacy of adjunctive hyperbaric oxygen therapy in the treatment of hidradenitis suppurativa. |
International journal of dermatology. 2016;55(2):232-7. |
Hydradenitis |
Wound healing |
HS | |
Thistlethwaite KR | Finlayson KJ | Cooper PD | The effectiveness of hyperbaric oxygen therapy for healing chronic venous leg ulcers: A randomized, double-blind, placebo-controlled trial. | Wound Repair and Regeneration. 2018 Jul;26(4):324-31 | Leg ulcer | Venous | Wound healing |
Thistlethwaite KR | Finlayson KJ | Cooper PD | The Effectiveness of Hyperbaric Oxygen Therapy for Healing Chronic Venous Leg Ulcers: A Randomized, Double-Blind, Placebo-Controlled Trial. | Journal of Vascular Surgery: Venous and Lymphatic Disorders. 2019 May 1;7(3):466 | Leg ulcer | Venous | Wound healing |
Inflammatory Bowel Disease
Buckey JC |
Raffals LE |
Hyperbaric oxygen therapy is well tolerated and effective for ulcerative colitis patients hospitalized for moderate–severe flares: |
The American Journal of Gastroenterology 2018; Feb 16:1. |
Ulcerative Colitis |
Steroids |
Hospitalisation | |
Hultgren E |
Arnell P |
Hyperbaric oxygen therapy does not improve the effects of standardized treatment in a severe attack of ulcerative colitis: a prospective randomized study. |
Scand J Gastroenterol 2013; 48:1033-40 |
Ulcerative colitis |
Steroids |
Flare-up |