Ottria
Hyperbaric oxygen may improve gingival health in healthy volunteers
Clinical Bottom Line:
1. None |
Citation/s:1. Ottria L, Tettamanti L, Gargari M, Valente G, Pacini V, Costanzo C. Hyperbaric oxygen therapy (HBOT) and peridontal health. Journal of biological regulators and homeostatic agents. 2018;32(2 Suppl. 1):217-21.
Lead author's name and fax: Liliana Ottria: lilianaottria@gmail.com
Three-part Clinical Question:For otherwise healthy adults, does the application of hyperbaric oxygen compared to no specific treatment result in better health of the gingiva?
Search Terms: Periodontitis, dental health, dentistry
The Study:Double-blinded concealed randomised controlled trial with intention-to-treat.
The Study Patients: Healthy divers with no history of periodontal disease.
Control group (N = 4; 4 analysed): Air breathing at 2.5 ATA for 65 minutes daily to a total of 25 sessions plus or minus five sessions.
Experimental group (N = 4; 4 analysed): As above but breathing 100% oxygen.
The Evidence:
Measure |
Sham Group |
HBO Group |
Difference |
95% CI | ||
Mean |
SD |
Mean |
SD | |||
Gingival Index (0 normal to 3 severe) |
1.4 |
0.10 |
1.4 |
0.15 |
0.0 |
-0.028 to 0.028 |
Full mouth plaque score (% of tooth surfaces with plaque) |
69.5 |
20.0 |
81.3 |
16.2 |
-11.8 |
-584 to 561 |
Comments:
1.Tiny study to no obvious purpose.
2. Poorly reported with several unexplained acronyms. The changes reported here were described as 'massive improvements' with hyperbaric oxygen but there are no statistical differences between groups (my stats).
Appraised by:Mike Bennett m.bennett@unsw.edu.au ; Tuesday, 14 September 2021
Kill or Update By: September 2025