Stiegler
No difference in tinnitus outcome between two hyperbaric oxygen protocols
Clinical Bottom Line:
|
1. There was no difference in outcome depending on the HBOT protocol |
Citation/s:1. Stiegler P, Matzi V, Lipp C, Kontaxis A, Klemen H, Walch C, Smolle-Jüttner F. Hyperbaric oxygen (HBO2) in tinnitus: influence of psychological factors ontreatment results? Undersea Hyperb Med. 2006 Nov-Dec;33(6):429-37.
Lead author's name and fax: Stiegler: None given
Three-part Clinical Question:For adult patients with tinnitus, does treatment with hyperbaric oxygen at 2.2 ATA compared to 2.5 ATA result in any improvement in outcome?
Search Terms: Tinnitus, hyperbaric protocol
The Study:Non-blinded randomised controlled trial without intention-to-treat.
The Study Patients: Adult patients where a decision has been made to treat with hyperbaric oxygen therapy
Control group (N = 156; 156 analysed): 100% oxygen treatments at 2.2ATA for 60 minutes daily for 15 consecutive days
Experimental group (N = 156; 156 analysed): Methods as above but at 2.5ATA.
The Evidence:
Outcome |
Time to Outcome |
2.2 ATA rate |
2.5 ATA rate |
Relative risk reduction |
Absolute risk difference |
NNT |
Improved or resolved after treatment |
1 month |
0.49 |
0.48 |
2% |
0.01 |
83 |
95% CIs: |
-20% to 25% |
-0.10 to 0.12 |
NNT = 8 to INF; NNH = 10 to INF | |||
Comments:
1. 360 patients treated in the whole cohort, but only 312 had outcomes recorded. It is not clear why.
2. No comparison made between HBOT and no HBOT in this study.
3. Randomisation method not specified and no other randomised outcomes reported.
4. Authors suggest the outcome is dependent on expectations for success prior to treatment
Appraised by:Mike Bennett m.bennett@unsw.edu.au; Sunday, 5 January 2020
Kill or Update By:January 2023
