Vadas

Breathing hyperbaric oxygen improved cognitive, motor and dual task performance compared to air breathing

1. Cognitive performance improved under hyperbaric oxygen conditions
2. Motor performance improved under hyperbaric oxygen conditions
3. Improvements both as sole tasks and when undertaken simultaneously
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Citation/s:
1. Vadas D, Kalichman L, Hadanny A, Efrati S. Hyperbaric oxygen environment can enhance brain activity and multitasking performance. Frontiers in Integrative Neuroscience. 2017 Sep 27;11:25.
Lead author's name and fax: Dor Vadas: dorvadas@gmail.com

Three-part Clinical Question:For the human brain, does breathing hyperbaric oxygen, compared to air breathing, enhance the performance of cognitive task and motor tasks?
Search Terms: Dual tasking, brain activity, oxygen limitation

The Study:
Double-blinded randomised controlled trial with intention-to-treat.
The Study Patients: Healthy adult volunteers
Control group (N = 24; 22 analysed): Air breathing at 1 ATA in a hyperbaric chamber for 45 minutes to simulate true hyperbaric exposure.
Experimental group (N = 24; 22 analysed): As above but breathing 100% oxygen at 2ATA

The Evidence:

Measure

Sham Group

HBO Group

Difference

95% CI

Mean

SD

Mean

SD

Symbol Digit Mobility Test (correct - incorrect answers)

40.2

9.8

43.9

11.6

3.7

-73.9 to 66.5

Bean Transfer Test (number in 30 seconds)

83.8

9.3

89.3

11.5

5.5

-72.1 to 61.0

SDMT as dual task

35.2

10.8

38.7

11.7

3.5

-80.6 to 73.6

BTT as dual task

51.4

14.7

56

14.2

4.6

-131.7 to 122.5

Comments:
1. Crossover study with sham procedure
2. The authors did not test the success of the sham procedure and the results may depend on that success
3. The authors conclude the performance of these tasks is limited by the availability of oxygen to the brain.                                                                          4. The practical significance of the differences measured is not clear, nor is any dose-response relationship.                                                                        5. The figures here are obtained using a t-test. The authors appropriately used paired t-test and found all these differences to statistically significant.

Appraised by:Mike Bennett POWH m.bennett@unsw.edu.au; Monday, 20 January 2020
Kill or Update By: January 2024

 

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