Difference between revisions of "Lafere"
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| − | <span style="line-height:normal">'''<span style="font-size:18.0pt"><span style="font-family: | + | <span style="line-height:normal">'''<span style="font-size:18.0pt"><span style="font-family:"><span style="color:black">Critical flicker fusion frequency testing shows similar changes at a measure of cognitive performance and may be a useful tool to warn of early nitrogen narcosis.</span></span></span>'''</span> |
| − | <span style="line-height:normal">'''<span style="font-size:14.0pt"><span style="font-family: | + | <span style="line-height:normal">'''<span style="font-size:14.0pt"><span style="font-family:"><span style="color:black">Clinical Bottom Line</span></span></span>'''</span> |
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| − | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family: | + | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:">1. Critical flicker fusion frequency could be a measure of cognitive decrement due to inert gas narcosis in divers.</span></span>'''</span> |
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| − | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family: | + | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">Citation/s:</span></span></span>'''<span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">1.Lafère P, Hemelryck W, Germonpré P, Matity L, Guerrero F, Balestra C. Early detection of diving-related cognitive impairment of different nitrogen-oxygen gas mixtures using critical flicker fusion frequency. Diving Hyperb. Med. 2019 Jun 1;49:119-26.<br/> '''Lead author's name and fax: '''Pierre Lafere doc.lafere@sfr.fr</span></span></span></span> |
| − | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family: | + | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">Three-part Clinical Question:</span></span></span>'''<span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">For adult divers, does cognitive performance vary under different conditions and can Critical Flicker Fusion Frequency (CFFF) serve as an indicator of threatened cognitive performance.<br/> '''Search Terms:''' Critical Flicker Fusion Frequency; Inert Gas Narcosis; cognitive testing</span></span></span></span> |
| − | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family: | + | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">The Study:</span></span></span>'''<span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">Double-blinded crossover concealed randomised controlled trial with intention-to-treat.<br/> '''The Study Patients:''' Fit volunteer divers.<br/> '''Control group''' (N = 8; analysed): Dry chamber dive breathing compressed air to 30 msw for 22 minutes<br/> '''Experimental group''' (N = 8; analysed): As above but breathing 40% oxygen (EAN).</span></span></span></span> |
| − | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family: | + | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">The Evidence:</span></span></span>'''</span> |
| − | <span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family: | + | <span style="line-height:normal"><span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">Multiple regression and ANOVA results given in paper.</span></span></span></span> |
| − | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family: | + | <span style="line-height:normal">'''<span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">Comments:</span></span></span>'''<br/> <span style="font-size:12.0pt"><span style="font-family:"><span style="color:black">1. Many outcomes subject to wide statistical analysis. No simple event or mean -based outcomes.<br/> 2. CFFF and a measure of cognitive performance broadly agree and suggest a decline in cognition at depth that may be assessable with CFFF.<br/> 3. Oxygen-dependent activation of the prefrontal cortex accompanies these changes.</span></span></span></span> <span style="font-size:12.0pt"><span style="line-height:107%"><span style="font-family:"><span style="color:black">Appraised by: Mike Bennett ; Sunday, 2 August 2020<br/> Email: m.bennett@unsw.edu.au<br/> '''Kill or Update By:''' August 2024</span></span></span></span> |
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Latest revision as of 22:28, 2 August 2020
Critical flicker fusion frequency testing shows similar changes at a measure of cognitive performance and may be a useful tool to warn of early nitrogen narcosis.
Clinical Bottom Line
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1. Critical flicker fusion frequency could be a measure of cognitive decrement due to inert gas narcosis in divers. |
Citation/s:1.Lafère P, Hemelryck W, Germonpré P, Matity L, Guerrero F, Balestra C. Early detection of diving-related cognitive impairment of different nitrogen-oxygen gas mixtures using critical flicker fusion frequency. Diving Hyperb. Med. 2019 Jun 1;49:119-26.
Lead author's name and fax: Pierre Lafere doc.lafere@sfr.fr
Three-part Clinical Question:For adult divers, does cognitive performance vary under different conditions and can Critical Flicker Fusion Frequency (CFFF) serve as an indicator of threatened cognitive performance.
Search Terms: Critical Flicker Fusion Frequency; Inert Gas Narcosis; cognitive testing
The Study:Double-blinded crossover concealed randomised controlled trial with intention-to-treat.
The Study Patients: Fit volunteer divers.
Control group (N = 8; analysed): Dry chamber dive breathing compressed air to 30 msw for 22 minutes
Experimental group (N = 8; analysed): As above but breathing 40% oxygen (EAN).
The Evidence:
Multiple regression and ANOVA results given in paper.
Comments:
1. Many outcomes subject to wide statistical analysis. No simple event or mean -based outcomes.
2. CFFF and a measure of cognitive performance broadly agree and suggest a decline in cognition at depth that may be assessable with CFFF.
3. Oxygen-dependent activation of the prefrontal cortex accompanies these changes. Appraised by: Mike Bennett ; Sunday, 2 August 2020
Email: m.bennett@unsw.edu.au
Kill or Update By: August 2024
