Difference between revisions of "Senol"
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| + | <span style="font-size:x-large;">'''Hyperbaric oxygenation did not improve post-dural puncture headache after spinal anaesthesia. '''</span> | ||
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| + | <span style="font-size:large;">'''1. Hyperbaric oxygen did not reduce pain scores compared to a sham procedure at any time between one and five days '''</span> | ||
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| + | '''Citation/s: '''1. Senol MG, Kendirli MT, Sen A, Karadurmus N, Kendirli N, Sen H, Saracoglu M. Efficacy of hyperbaric oxygen therapy in post-dural puncture headache. TURKIYE KLINIKLERI TIP BILIMLERI DERGISI. 2009 Dec 1;29(6):1618-22. <br/> '''Lead author's name and fax:''' Mehmet Senol: mgsenol@yahoo.com | ||
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| + | '''Three-part Clinical Question:''' Does hyperbaric oxygen improve post lumbar puncture headache? <br/> '''Search Terms:''' Post-dural-puncture headache; spinal headache; normobaric | ||
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| + | '''The Study: '''<br/> Double-blinded randomised controlled trial with intention-to-treat. <br/> '''The Study Patients:''' Patients complaining of post dural puncture headache after spinal anaesthesia. <br/> '''Control group''' (N = 10; 10 analysed): Nil specific therapy - air-breathing only.as a sham procedure daily for six days <br/> '''Experimental group''' (N = 10; 10 analysed): As above but 100% oxygen breathing at 2.0 ATA for 45 minutes. | ||
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| + | '''The Evidence: ''' | ||
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| + | {| border="1" data-tablelook="1184" data-tablestyle="MsoNormalTable" | ||
| + | |- role="row" | ||
| + | | colspan="1" data-celllook="4369" role="rowheader" rowspan="2" | <p style="text-align: center;">M'''easure '''</p> | ||
| + | | colspan="2" data-celllook="273" role="columnheader" | <p style="text-align: center;">'''Sham Group '''</p> | ||
| + | | colspan="2" data-celllook="273" role="columnheader" | <p style="text-align: center;">'''HBOT Group '''</p> | ||
| + | | colspan="1" data-celllook="273" role="columnheader" rowspan="2" | <p style="text-align: center;">'''Difference '''</p> | ||
| + | | colspan="1" data-celllook="273" role="columnheader" rowspan="2" | <p style="text-align: center;">'''95% CI '''</p> | ||
| + | |- role="row" | ||
| + | | data-celllook="272" | <p style="text-align: center;">'''Mean '''</p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">'''SD '''</p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">'''Mean '''</p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">'''SD '''</p> | ||
| + | |- role="row" | ||
| + | | data-celllook="4368" role="rowheader" | | ||
| + | '''Mean pain score (0 no pain to 100 maximum pain) Day 1 ''' | ||
| + | |||
| + | | data-celllook="272" | <p style="text-align: center;">50.1 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">24.8 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">44.2 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">21.4 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">5.9 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">-498.2 to 51.0 </p> | ||
| + | |- role="row" | ||
| + | | data-celllook="4368" role="rowheader" | | ||
| + | '''Mean pain score (0 no pain to 100 maximum pain) Day 2 ''' | ||
| + | |||
| + | | data-celllook="272" | <p style="text-align: center;">32.4 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">20.8 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">27.8 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">21.7 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">4.6 </p> | ||
| + | | data-celllook="272" | <p style="text-align: center;">-419.9 to 429.1 </p> | ||
| + | |} | ||
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| + | '''Comments: '''<br/> 1, Abstract and limited translation only - full translation of the paper would be welcome! <br/> 2. Small measured benefits from hyperbaric oxygen cannot be ruled out in this underpowered study. | ||
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| + | '''Appraised by''': Mike Bennett m.bennett@unsw.edu.au; Wednesday, 5 February 2020 <br/> '''Kill or Update By''': February 2021 | ||
Revision as of 00:45, 7 February 2020
Hyperbaric oxygenation did not improve post-dural puncture headache after spinal anaesthesia.
1. Hyperbaric oxygen did not reduce pain scores compared to a sham procedure at any time between one and five days
Citation/s: 1. Senol MG, Kendirli MT, Sen A, Karadurmus N, Kendirli N, Sen H, Saracoglu M. Efficacy of hyperbaric oxygen therapy in post-dural puncture headache. TURKIYE KLINIKLERI TIP BILIMLERI DERGISI. 2009 Dec 1;29(6):1618-22.
Lead author's name and fax: Mehmet Senol: mgsenol@yahoo.com
Three-part Clinical Question: Does hyperbaric oxygen improve post lumbar puncture headache?
Search Terms: Post-dural-puncture headache; spinal headache; normobaric
The Study:
Double-blinded randomised controlled trial with intention-to-treat.
The Study Patients: Patients complaining of post dural puncture headache after spinal anaesthesia.
Control group (N = 10; 10 analysed): Nil specific therapy - air-breathing only.as a sham procedure daily for six days
Experimental group (N = 10; 10 analysed): As above but 100% oxygen breathing at 2.0 ATA for 45 minutes.
The Evidence:
Measure |
Sham Group |
HBOT Group |
Difference |
95% CI | ||
Mean |
SD |
Mean |
SD | |||
|
Mean pain score (0 no pain to 100 maximum pain) Day 1 |
50.1 |
24.8 |
44.2 |
21.4 |
5.9 |
-498.2 to 51.0 |
|
Mean pain score (0 no pain to 100 maximum pain) Day 2 |
32.4 |
20.8 |
27.8 |
21.7 |
4.6 |
-419.9 to 429.1 |
Comments:
1, Abstract and limited translation only - full translation of the paper would be welcome!
2. Small measured benefits from hyperbaric oxygen cannot be ruled out in this underpowered study.
Appraised by: Mike Bennett m.bennett@unsw.edu.au; Wednesday, 5 February 2020
Kill or Update By: February 2021
